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R&D

Personnel(Key Personnel & Advisors)

aptech

Superb research and development personnel

aptech

Professional advisory groups composed of
domestic and foreign experts

A field of research

aptech

Overcoming the shortcomings of the protein production process,
Develop core technologies that can dramatically improve productivity
by simplifying complex muilt-step processes

Development of safest and most productive technology for human
milk oligosaccharide by using Corynebacterium glutamicum as a host
instead of E.coli

Intellectual Property

19 domestic patents and 24 international patents

Production and new use patents for
breat milk osaccharide

(Intl PCT, AU, CA, CN, EU, IN, JP, KR, US 등)

manufacturing compound protein patent

(Korea, China, Japan, Europe)

Securing the Mamstamine brand

Type Location Application/Approval Number
Patent Korea Application 5
Approval 14
Overseas Application 18
Approval 6
Trademark Korea Application 1
Approval 10
Overseas Application 0
Approval 4

R&D Performance

R&D Task & Dateils Development Period Business Scale Remarks
Delvelopment of manufacturing process of nano disk membrane stuctured protein 2007.06 ~ 2009.05 KRW 200,000,000 Completion
Delvelopment of commercialization
technology of monoclonal antibody affinity ligand
2007.10 ~ 2009.09 KRW 433,300,000 Completion
(Chosen as comapany with outstranding performance)
commercialization of
Herceptin Biosimilars
2009.07 ~ 2010.06 KRW 9,322,000,000 Completion
Developed thrombocytopenic
oral protein therapeutics using
TPO Variants (Host organization)
2010.06 ~ 2013.12 KRW 840,000,000 Completion
Bioproduction of long-chain dicarboxylic acids form
fatty acides and lipids
2013.06 ~ 2018.05 KRW 4,332,000,000 Completion
Delvelopment of high
density lipoprotein like
nanoparitcle of Epothilone B
2013.06 ~ 2015.05 KRW 830,000,000 Completion
Bio-based production of isobutylene 2014.06 ~ 2019.05 KRW 5,166,665,000 Completion
Process Delvelopment
for Modified Entolimod
2014.06 ~ 2019.05 KRW 8,000,000,000 Completion
Development of Fucosyllactose
for Infant Formula
2017.04 ~ 2019.12 KRW 2,125,192,000 Completion
Biological production of
D-ribose and its application to foods development
2018.09 ~ 2022.05 KRW 2,529,952,000 In Progress

HMO Technologies

Patent name Applicant Application/
Registration
Date of resistration Registration
number
Production method of 2'-fucosyl lactose using fucose transferase
derived form pseudofedobacter saltans
AP Technologies Approved 2015
-08-06
10154
4184
Cosmetic composition for skin irritation alleviation with 2'-fucosyllactose AP Technologies Approved 2017
-04-24
10173
1263
Method for increase stability, survival rate, acid resistance, bile resistance
of lactic acid bacteria width 2'-FL or 3'-FL, human milk oligosaccharide
AP Technologies Filed 2019
-11-25
10205
0522
Method for production of lactic acid bacteria with human milk
oligosaccharide for increasing probiotic activity
AP Technologies Filed 2018
-09-12
10201
4925
Composition for synbiotics,probiotic width human milk oligosaccharide AP Technologies Filed 2019
-04-22
10197
2925

Protein Technologies

Patent name Applicant Application/
Registration
Date of resistration Registration
number
Process for preparation of polypeptides of interest from fusion polypeptides AP Technologies Approved 2005
-12-02
10053
5265
Method for preparation of nanostructured complex if hydrophobic drug AP Technologies
Sungkyunkwan University Industry-Unibersity
cooperation foundation
Approved 2012
-03-21
10113
1202
Thrombopoientin developed with mass production for oral dosage
and mass production process thereof
AP Technologies Approved 2017
-12-26
10181
4048
Antibody binding affinity ligan with advaned alkali resistance AP Technologies Approved 2019
-06-21
10199
3845
New ketol-acid reductoisomerase with a cofactor preference to NADH developed AP Technologies
Korea University Industry-Unibersity cooperation foundation
Approved 2019
-03-14
10196
0501
PROCESS FOR PURIFICATION OF RECOMBINANT ADENOVIRUS TYPE 3 FIBER POLYPEPTIDE AP Technologies
Samayng Bio Pharm Co.,Ltd
Approved 2018
-10-02
10190
6319
A recombinate organism enhancend furfural tolerance and method
for production of isobytanol using the same
AP Technologies
Konkuk University Industry-Unibersity cooperation foundation
Approved 2018
-08-02
10188
6186
Method for isolation of L-arabinose by arabinofuranosidase
treatment with addition of KCI or NaCI
AP Technologies
Chungbuk National University Industry-Unibersity cooperation foundation
Approved 2010
-09-14
10098
3324

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